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[80.233.244.141]) by mx.google.com with ESMTPS id ffacd0b85a97d-39d89385addsi665673f8f.248.2025.04.09.03.28.03 for (version=TLS1_3 cipher=TLS_AES_256_GCM_SHA384 bits=256/256); Wed, 09 Apr 2025 03:28:03 -0700 (PDT) Received-SPF: pass (google.com: domain of bounce-mktg_13324753.3_8n8c74mt44nikeydu5smziv56@pds.pdrserv.vitrotem.com designates 80.233.244.141 as permitted sender) client-ip=80.233.244.141; Authentication-Results: mx.google.com; dkim=pass header.i=@vitrotem.com header.s=pdn1evcb3421 header.b=6YP+rhGU; dkim=pass header.i=@pdrserv.com header.s=pd1 header.b=0EPLFcoQ; spf=pass (google.com: domain of bounce-mktg_13324753.3_8n8c74mt44nikeydu5smziv56@pds.pdrserv.vitrotem.com designates 80.233.244.141 as permitted sender) smtp.mailfrom=bounce-mktg_13324753.3_8n8c74mt44nikeydu5smziv56@pds.pdrserv.vitrotem.com; dmarc=pass (p=NONE sp=NONE dis=NONE) header.from=vitrotem.com DKIM-Signature: v=1; a=rsa-sha256; c=relaxed/relaxed; s=pdn1evcb3421; d=vitrotem.com; h=List-Unsubscribe:List-Unsubscribe-Post:From:To:Reply-To:Subject:Message-ID: Date:MIME-Version:Content-Type; i=info@vitrotem.com; bh=XT30qsIBfd62/+NBVpeO94g70WLp3ZMFCL5mG4FCJVo=; b=6YP+rhGUidZW2L+eeZp1WhApNSXafC9W2NMB/Fs4/LsEFig0JG+TZmeLc6AjMz2aSl79N3MdP5P0 WH1a0WQwguPNl2/5C4iDWiD1+v6fRhQQ4TZ6ZAz0VJh/YEx/5Zv7/OK6gbkdZ+uXule+6wDIFsAs eULM6fwnCqD3EotURDpJor8h9dUl1fN7BSD27crpXy5nILAFt9VQkMcdevLYJG+OI5x7wVoG9vFj Nlx/pKkaAu3b0mK/7NVbOpAdqgCncNu3YzaWi7sy2BalJnQsoCwUqZxOxSZ145/CKoFl4SRGguqt gXksQGZczHBGRU+Bo0TKfAPRV7ocPvsXS0ZHLQ== DKIM-Signature: v=1; a=rsa-sha256; c=relaxed/relaxed; s=pd1; d=pdrserv.com; h=List-Unsubscribe:List-Unsubscribe-Post:From:To:Reply-To:Subject:Message-ID: Date:MIME-Version:Content-Type; bh=XT30qsIBfd62/+NBVpeO94g70WLp3ZMFCL5mG4FCJVo=; b=0EPLFcoQF2uWQG7577d3w2o+yYDokJJgEL6GLY9rsOQ/41AeOjuLgSAS+joY+DOOI2/GM7ptzTXe V3xzBGzq8ycl/0PVGy3n+Nbb2pvzvvamesUShWv5DzpkxrUCvnTlgCSMlJ5lu946cCqiqB2MKt9v Nh9USb2kclHVTTFheIgf6kcDOcslp8azu2Ebq5W635F5DXJnUYPCQmHSie3Sas/8Ga2LXmpqPZes EQ9k+HFdmDHnAjKy2oWNC1GDs4NWvGzZ7B3H/iudAxNNa13xH9mI9T/aPe8Xqsejuc6PUp2tJygi XYh6sdF0jTmfvfkH0jKPMSDUWczzTpDAuEWwUg== Received: by mail141.pd2.onpdr.com id hup5r6393dc6 for ; Wed, 9 Apr 2025 10:27:43 +0000 (envelope-from ) List-Unsubscribe: , <> List-Unsubscribe-Post: List-Unsubscribe=One-Click From: Hans from VitroTEM To: info@vitrotem.com Reply-To: info@vitrotem.com Subject: Enhance Your Research with Ultra-Thin Graphene Liquid Cells Message-ID: <9207a728-fd5f-50e8-a476-6bbdf227892a@pds.pdrserv.vitrotem.com> Date: Wed, 09 Apr 2025 10:27:43 +0000 MIME-Version: 1.0 Content-Type: multipart/alternative; boundary="--_pd-546166daabbda358-Part_1" ----_pd-546166daabbda358-Part_1 Content-Type: text/plain; charset=utf-8 Content-Transfer-Encoding: quoted-printable Naiad revolutionizes Graphene Liquid Cell (GLC) technology, offering the = most electron-transparent window for liquid-phase TEM imaging. https://vitrotem.com/ Boost Your Research Productivity with Naiad =E2=80=8A Naiad revolutionizes Graphene Liquid Cell (GLC) technology, = offering the most electron-transparent window for liquid-phase TEM imaging.= This advanced platform enables real-time, high-resolution imaging for = diverse applications, from biological research to nanomaterial analysis. Key Benefits * Atomic-Scale Resolution =E2=80=93 Graphene=E2=80=99s = ultra-thin, electron-transparent nature enables precise imaging in = liquid environments. * Radiation Protection =E2=80=93 Absorbs & scatters = electrons, minimizing damage to sensitive materials. * High Signal-to-Noise Ratio (SNR) =E2=80=93 Reduces scattering, enhancing= image clarity & chemical analysis. * Real-Time Observation =E2=80=93 = Captures nanoparticle growth, dissolution & crystallization for deeper = material insights. * Chemical Stability =E2=80=93 Impermeable graphene = preserves liquid samples without contamination or evaporation. * Superior Freezing Efficiency =E2=80=93 Reduced thermal mass improves = freezing; HeLa cells freeze vitreously without cryoprotectants, yielding= =E2=80=9Cperfect ice=E2=80=9D and =E2=80=9Cperfect lamella.=E2=80=9D * Enhanced Thermal Conductivity =E2=80=93 Graphene=E2=80=99s exceptional = heat conductivity boosts freezing performance. * Clear Targeting = =E2=80=93 Eliminates excess liquid, simplifying cryoET sample preparation. * Better Cell Viability =E2=80=93 Graphene encapsulation = prevents damage, maintaining cell health for extended periods. * HPF Compatibility =E2=80=93 Protects samples from 2MP effects and may = reduce HPF dependency for mammalian cells. * In Situ Compatibility = =E2=80=93 Seamlessly integrates with TEM for operando studies of chemical & physical processes. * Broad Applications =E2=80=93 = Supports colloidal science, life sciences, energy research, and = environmental studies. Naiad simplifies GLC fabrication, eliminating = specialized sample holders while ensuring precision, reliability, and = efficiency in TEM imaging READ MORE https://vitrotem.com/products/ Latest collaborations =E2=80=8A Nottingham University =C2=A0 This group is using Naiad for Single Particle Analyses in Life science Maastricht University (Ron Heeren) =C2=A0 Using Naiad for nanomedicine = and biomedical research. Janelia Farm HHMI (Zhiheng Yu) =C2=A0 Janelia Research Institute Sterling, VA, USA Harvard University =C2=A0 Harvard Center for Nanoscale Systems Life Sciences single particle analysis= . This group is using Naiad for Single Particle Analyses in Life science University of Nijmegen (Radboud University Medical Center)=C2=A0 =C2=A0 Courtesy of Sommerdijk group, Radboud MC Nijmegen A Cryo-to-Liquid Phase Correlative Light Electron Microscopy Workflow for = the Visualization of Biological Processes in Graphene Liquid Cells L. Rutten and his coworkers used Naiad for GLC preparation and published a = nice paper. The observation of the complexation of fetuin-A with = calcium/phosphate, under biological relevant conditions was successfully = achieved. READ PAPER https://doi.org/10.1093/micmic/ozad067.1002 Graphene Liquid cells prepared with automated Naiad =E2=80=8A Collagen fibril in SiN liquid cell Collagen fibril in Graphene liquid cell Ferritin particles Magnetic particles GLC-based cryo-EM for = Coxsackievirus=C2=A0 2.2 =C3=85 from 140,000 particles In GLCs, the conventionally inescapable air-liquid interface is replaced on= both sides with a graphene-liquid interface. As a results, virus particles= populate all of the regions of interest, no longer repulsed by the = air-liquid interface. Considerable attention is currently going to the = potential of the graphene-liquid interface to resolve orientation issues = experienced for many classes of proteins. The possibility to modify the = graphene surface offers a means to influence the orientation of particles = in the GLC layer. We are excited to welcome Hans Radhoe as our new Chief = Commercial Officer =E2=80=8A Hans brings a wealth of experience and a = strong commercial background to our team. He completed his Bachelor's = degree in Biotechnology at the Polytechnical Faculty in Delft and earned a = Master's degree in Environmental Management from the Open University in = Heerlen, The Netherlands. He served as the Sales Director at Amsterdam Scientific Instruments (ASI), a spin-off company from Nikhef (National Institute for Subatomic Physics), the Dutch research institute = for particle physics. Most recently, Hans was the Vice President of Sales = at DENSsolutions, a company specializing in advanced electron microscopy = solutions. At Vitrotem, Hans will focus on identifying growth opportunities= for the company and leading various aspects of the sales process, = including prospecting, go-to-market strategies, and customer relationship = management Hans Radhoe Chief Commercial Officer Unlock the future of graphene liquid cell fabrication with Naiad =C2=A0 =E2=80=8A =C2=A0 Explore its potential today and revolutionize your = research in biology, nanotechnology, and materials science! VISIT WEBSITE AND SCHEDULE A DEMO! https://vitrotem.com/contact/ https://x.com/vitrotem https://www.linkedin.com/company/vitrotem/https://ww= w.youtube.com/channel/UCz94uyWgc0cq6k14C_DmX0Q vitroTEM Sciencepark 106, Amsterdam, Noord Holland, 1098XG, = Netherlands No longer interested in receiving emails? Click here to = unsubscribe ----_pd-546166daabbda358-Part_1 Content-Type: text/html; charset=utf-8 Content-Transfer-Encoding: quoted-printable
Naiad revolutionizes Graphene Liquid Cell (GLC) technology, offering= the most electron-transparent window for liquid-phase TEM imaging.
3D"Logo"

Boost Your Research Productivity with = Naiad

=E2=80=8A

Naiad revolutionizes Graphene = Liquid Cell (GLC) technology, offering the most electron-transparent window= for liquid-phase TEM imaging. This advanced platform enables real-time, = high-resolution imaging for diverse applications, from biological research = to nanomaterial analysis.

3D"Image"

Key = Benefits
  • Atomic-Scale Resolution =E2=80=93 Graphene=E2=80=99s = ultra-thin, electron-transparent nature enables precise imaging in liquid = environments.
  • Radiation Protection =E2=80=93 = Absorbs & scatters electrons, minimizing damage to sensitive materials.=
  • High Signal-to-Noise Ratio (SNR) =E2=80=93 = Reduces scattering, enhancing image clarity & chemical analysis.=
  • Real-Time Observation =E2=80=93 Captures = nanoparticle growth, dissolution & crystallization for deeper material = insights.
  • Chemical Stability =E2=80=93 Impermeable= graphene preserves liquid samples without contamination or evaporation.=
  • Superior Freezing Efficiency =E2=80=93 Reduced = thermal mass improves freezing; HeLa cells freeze vitreously without = cryoprotectants, yielding =E2=80=9Cperfect ice=E2=80=9D and = =E2=80=9Cperfect lamella.=E2=80=9D
  • Enhanced Thermal = Conductivity =E2=80=93 Graphene=E2=80=99s exceptional heat = conductivity boosts freezing performance.
  • Clear Targeting = =E2=80=93 Eliminates excess liquid, simplifying cryoET sample = preparation.
  • Better Cell Viability =E2=80=93 = Graphene encapsulation prevents damage, maintaining cell health = for extended periods.
  • HPF Compatibility =E2=80=93 = Protects samples from 2MP effects and may reduce HPF dependency = for mammalian cells.
  • In Situ Compatibility = =E2=80=93 Seamlessly integrates with TEM for operando studies of chemical = & physical processes.
  • Broad Applications = =E2=80=93 Supports colloidal science, life sciences, energy = research, and environmental studies.
<= /tr>

Naiad simplifies GLC = fabrication, eliminating specialized sample holders while ensuring = precision, reliability, and efficiency in TEM imaging

READ = MORE

Latest collaborations

=
=E2=80=8A
3D"Image"

Nottingham University

 

This group is using Naiad for Single Particle Analyses in Life = science

3D"Image"

Maastricht University (Ron = Heeren)

 

Using Naiad for nanomedicine and biomedical research.=

3D"Image"

Janelia Farm HHMI (Zhiheng Yu)

 

Janelia Research Institute Sterling, VA, USA

3D"Image"

Harvard University

 

Harvard Center for Nanoscale Systems Life Sciences single particle = analysis. This group is using Naiad for Single Particle Analyses in Life = science

3D"Image"

University of Nijmegen (Radboud University Medical = Center) 

 

Courtesy of Sommerdijk group, Radboud MC = Nijmegen

A = Cryo-to-Liquid Phase Correlative Light Electron Microscopy Workflow for the= Visualization of Biological Processes in Graphene Liquid = Cells

L. Rutten and his coworkers = used Naiad for GLC preparation and published a nice paper. The observation = of the complexation of fetuin-A with calcium/phosphate, under biological = relevant conditions was successfully achieved.

READ = PAPER
3D"Image"

Graphene Liquid cells prepared with = automated Naiad

=E2=80=8A
3D""
<= /td>

Collagen fibril in = SiN liquid cell

Collagen fibril in = Graphene liquid cell

3D""
<= /td>
3D""

Ferritin particles

= 3D""
<= table class=3D"text_block block-2" width=3D"100%" border=3D"0" = cellpadding=3D"0" cellspacing=3D"0" role=3D"presentation" = style=3D"mso-table-lspace:0;mso-table-rspace:0;word-break:break-word">

Magnetic particles

3D""

GLC-based cryo-EM for Coxsackievirus 

= 3D""
<= table class=3D"text_block block-2" width=3D"100%" border=3D"0" = cellpadding=3D"0" cellspacing=3D"0" role=3D"presentation" = style=3D"mso-table-lspace:0;mso-table-rspace:0;word-break:break-word">

2.2 =C3=85 from 140,000 particles

In GLCs, the conventionally = inescapable air-liquid interface is replaced on both sides with a = graphene-liquid interface. As a results, virus particles populate all of = the regions of interest, no longer repulsed by the air-liquid interface. = Considerable attention is currently going to the potential of the = graphene-liquid interface to resolve orientation issues experienced for = many classes of proteins. The possibility to modify the graphene surface = offers a means to influence the orientation of particles in the GLC layer.

=

We are excited to welcome Hans Radhoe as our = new Chief Commercial Officer

=E2=80=8A
=
Hans brings a wealth of experience and a strong commercial background to = our team. He completed his Bachelor's degree in Biotechnology at the = Polytechnical Faculty in Delft and earned a Master's degree in = Environmental Management from the Open University in Heerlen, The = Netherlands. He served as the Sales Director at Amsterdam Scientific = Instruments (ASI), a spin-off company from Nikhef (National Institute for = Subatomic Physics), the Dutch research institute for particle physics. Most= recently, Hans was the Vice President of Sales at DENSsolutions, a company= specializing in advanced electron microscopy solutions. At Vitrotem, Hans = will focus on identifying growth opportunities for the company and leading = various aspects of the sales process, including prospecting, go-to-market = strategies, and customer relationship management

3D"Image"

Hans Radhoe

Chief Commercial = Officer

<= /table>

Unlock the future of graphene liquid cell fabrication with = Naiad

 

=E2=80=8A

 

Explore its potential today and revolutionize your research in = biology, nanotechnology, and materials science!

VISIT WEBSITE AND SCHEDULE A DEMO!=
<= /tbody>
3D"Twitter" 3D"LinkedIn"3D"YouTube"

vitroTEM

Sciencepark 106, Amsterdam, Noord Holland, 1098XG, = Netherlands


No longer interested in receiving emails= ? Click here to unsubscribe

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